THE NEGRI BODIES IN RABIES
نویسندگان
چکیده
منابع مشابه
The Negri Bodies in Rabies
1. The Negri bodies, as the etiological agent in rabies, present two general types or phases in morphology, in growth, and in reproduction. 2. These two phases are constantly cyclic in their development and correspond (1) to a multiplicative, or schizogonous, and (2) to a reproductive, or sporogonous, life cycle. 3. By the detailed study of these forms and their succeeding stages we are incline...
متن کاملEtymologia: Negri Bodies
in Ontario, Canada: management implications. J Wildl Dis. 2006;42:589–605. http://dx.doi.org/10.7589/0090-3558-42.3.589 27. Rosatte R, Sobey K, Donovan D, Allan M, Bruce L, Buchanan T, et al. Raccoon density and movements after population reduction to control rabies. J Wildl Manage. 2007; 71:2373–8. http://dx.doi.org/10.2193/2006-549 28. Rosatte R, Donovan D, Allan M, Howes LA, Silver A, Bennet...
متن کاملToll-Like Receptor 3 (TLR3) Plays a Major Role in the Formation of Rabies Virus Negri Bodies
Human neurons express the innate immune response receptor, Toll-like receptor 3 (TLR3). TLR3 levels are increased in pathological conditions such as brain virus infection. Here, we further investigated the production, cellular localisation, and function of neuronal TLR3 during neuronotropic rabies virus (RABV) infection in human neuronal cells. Following RABV infection, TLR3 is not only present...
متن کاملFunctional characterization of Negri bodies (NBs) in rabies virus-infected cells: Evidence that NBs are sites of viral transcription and replication.
Rabies virus infection induces the formation of cytoplasmic inclusion bodies that resemble Negri bodies found in the cytoplasm of some infected nerve cells. We have studied the morphogenesis and the role of these Negri body-like structures (NBLs) during viral infection. The results indicate that these spherical structures (one or two per cell in the initial stage of infection), composed of the ...
متن کاملThe Nature of the Negri Body
The Negri body is characteristic of the street rabies virus infection. Although there have been a number of studies on the problem of whether the Negri body consists of a reactive product of the cell brought about by the rabies virus multiplication or contains virus particles, the final answer is still lacking. Recently, several papers concerning the morphology of the rabies virus have revealed
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1913
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.17.1.29